Animal Models of Osteochondral Defect for Testing Biomaterials
نویسندگان
چکیده
منابع مشابه
Clinical results of multilayered biomaterials for osteochondral regeneration
Several techniques have been used during the years to treat chondral and osteochondral lesions. Among them, the emerging trend in the field of osteochondral regeneration is to treat the entire osteochondral unit by implanting cell-free scaffolds, which provide a three-dimensional support for the cell growth and may act themselves as stimuli for an "in situ" tissue regeneration. Various multi-la...
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The osteochondral defects caused by vigorous trauma or physical disease are difficult to be managed. Tissue engineering provides a possible option to regenerate the damaged osteochondral tissues. For osteochondral reconstruction, one intact scaffold should be considered to support the regeneration of both cartilage and subchondral bone. Therefore, the biphasic scaffolds with the mimic structure...
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OBJECTIVES We sought to determine if a durable bilayer implant composed of trabecular metal with autologous periosteum on top would be suitable to reconstitute large osteochondral defects. This design would allow for secure implant fixation, subsequent integration and remodeling. MATERIALS AND METHODS Adult sheep were randomly assigned to one of three groups (n = 8/group): 1. trabecular metal...
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ژورنال
عنوان ژورنال: Biochemistry Research International
سال: 2020
ISSN: 2090-2247,2090-2255
DOI: 10.1155/2020/9659412